In the late 22nd century, natural disasters continue unabated, ecosystems are destroyed, and epidemics persist. Infertility and sterility become common among people living in lands contaminated by radiation. But ironically, as the population decreases, the land gradually regains its greenness.Two hundred years later, in 2399, the remaining people on Earth create human clones, and those who are unable to have children due to infertility and sterility adopt clone children. Earth has now become a world where humans and clones coexist. The residential areas are mainly divided into three regions: Metro, a densely populated city of 100,000 inhabitants; Ghetto, impoverished areas outside the city center; and Reboot, a special district for reconstruction where the affluent are concentrated.

At the age of 13, Lea watches Honeybee and realizes that she is not a child born out of love but a cloned human created artificially. Ever since then, she has felt upset towards humans for their discrimination against clones. At the same time, she admires the uniqueness of humans, so she manipulates her medical records to participate in Honeybee as a human. Honeybee is a reality dating show produced by a private broadcasting company. It became popular among many dating shows for its unique requirement that the winning couple must conceive and raise a child together. This condition necessitates all participants to be fertile humans. Clones and their guardians strongly opposed the format, sparking a controversy that ironically brought even more attention to the show. Driven by the desire for a new civilization and a new generation, humans are enthusiastic about producing “real babies” through traditional means. Some viewers even argue that the show and its participants embody the most devoted form of love for humanity. The last remaining couple on the show is awarded various sponsorships to support them in the journey of having and raising their child.

Joyul, one of the participants in Honeybee, is extremely cautious about revealing her true identity. In fact, she is from Zero, one of the ghettos. Zero is often misunderstood as the most secluded region as it follows a policy of not allowing married couples, pregnant women, and clones and does not engage in tourism, unlike the surrounding ghettos. Joyul spends most of her days hunting with Mamoru. However, whenever she hears the cries of her prey in pain, she has a hard time accepting the human-centered society, even though she understands in her head that this is how humans and ecosystems coexist. Joyul struggles to comprehend Honeybee, the popular show that her twin sister Johwa is obsessed with. Since her mobility is limited due to her leg injury from an accident, Johwa spends time watching the show through a device called Tetra, which is reminiscent of smartphones from the past. Joyul finds the concept of the show, which exposes one’s privacy, creepy and dismisses it as a stupid human breeding show.

One day, Johwa goes missing, but two days later, she returns to Zero with an invitation to Honeybee. Johwa asks her sister to join the show. It turns out that Johwa had been longing to participate in the show and submitted an application. Now that she is confirmed as a participant, she cannot join the show since she is pregnant with a child whose father is unknown. Reluctantly, Joyul agrees to take her sister’s place, fearing that they could be kicked out of Zero if her sister’s pregnancy is known to the town.Thus, Joyul, Mamoru, and Lea conceal their identities and participate in the same season of Honeybee. Along the way, Lea develops an interest in Mamoru and starts following him around, only to discover an unusual relationship between Joyul and Mamoru. Can Joyul and Mamoru become the last remaining couple on Honeybee without their true intentions being revealed?